Table 2.
Multivariable analysis on the entire cohort (chemotherapy-treated and untreated). The analysis evaluated the association between the variables and distant recurrence
| Variablea | Comparison | Hazard ratio | P-value |
|---|---|---|---|
| (95% confidence intervals) | |||
| Size | ≥2 vs. <2 cm | 1.8 (1.0–3.3) | 0.04 |
| Nodal status | 1–3 positive nodes vs. N1mi | 0.86 (0.48–1.6) | 0.63 |
| RS Group | <18 vs. ≥31 | 0.23 (0.11–0.50) | 0.001 |
| 18–30 vs. ≥31 | 0.42 (0.20–0.86) |
RS Recurrence Score
a The RS group remained a significant variable (P < 0.001) when age and tumor grade were also included in the multivariable model