Table 1.
Autism spectrum disorders and medical disorders
| Authors | Year | Study size cases/controls | Age range (years) | Study design | Medical disorder | |
|---|---|---|---|---|---|---|
| Immunology | Jyonouchi et al. | 2008 | 26/212 | 1–18 | Cross-sectional | Atopy, asthma, allergy and immunodeficiency |
| MH Chen et al. | 2014 | 14,812/6994 | 1–14 | Case–control | Asthma, atopic dermatitis, allergic rhinitis, or allergic conjunctivitis | |
| Gentile et al. | 2014 | 54/46 | 3–9 | Cross-sectional | Antibody levels of HSV 1 and HSV 2 | |
| Puig–Alcatraz et al. | 2015 | 35/34 | 4–13 | Cross-sectional | Homocysteine levels | |
| Zerbo et al. | 2015 | 5565/27,825 | 3–26 | Case–control | Immune-mediated conditions | |
| Gastroenterology | Valicenti et al. | 2006 | 50/100 | 4–12 | Cross-sectional | Gastro-intestinal symptoms |
| Mouridsen et al. | 2010 | 118/336 | 0–57 | Case–control | Gastro-intestinal diseases | |
| Wang et al. | 2011 | 589/163 | 1–18 | Cross-sectional | Gastro-intestinal problems | |
| Chandler et al. | 2013 | 132/163 | 10–14 | Cross-sectional | Gastro-intestinal symptoms | |
| Mouridsen et al. | 2013 | 89/258 | 3–65 | Case–control | Gastro-intestinal diseases | |
| Von Gontard et al. | 2015 | 40/43 | 5–17 | Case–control | Gastro-intestinal symptoms | |
| Neurology | Mouridsen et al. | 2013 | 4180/general population | 4–31 | Cross-sectional | Epilepsy |
| Other medical disorders | Van Tongerloo et al. | 2012 | 49/81 | 8–16 | Case–control | Medical comorbidity and referrals by a general practitioner |
| Butwicka et al. | 2015 | 9262/468,036 | 1–30 | Case–control | Hypospadias |