Table 3.

Results of cox-regression models with different outcomes of glaucoma (see Fig. 2; in all models, controls were participants without iGVFL and without GON [n = 3548])

	iGVFL (n = 140)		GON (n = 299)		iGVFL and GON (n = 48)		iGVFL without GON (n = 92)		GON without iGVFL (n = 251)
	Hazard ratio (95% CI)	p	Hazard ratio (95% CI)	p	Hazard ratio (95% CI)	p	Hazard ratio (95% CI)	p	Hazard ratio (95% CI)	p
Age (years)	1.09 (1.06–1.12)	<0.001	1.11 (1.10–1.13)	<0.001	1.09 (1.04–1.14)	<0.001	1.09 (1.06–1.13)	<0.001	1.12 (1.10–1.14)	<0.001
Gender (f)	0.78 (0.56–1.10)	0.16	0.96 (0.76–1.21)	0.72	0.89 (0.49–1.60)	0.69	0.74 (0.49–1.12)	0.15	0.97 (0.75–1.25)	0.80
IOP (mmHg)	1.14 (1.10–1.19)	<0.001	1.11 (1.08–1.15)	<0.001	1.18 (1.11–1.24)	<0.001	1.13 (1.06–1.20)	<0.001	1.09 (1.05–1.13)	<0.001
IOP Rx	2.61 (1.35–5.04)	<0.01	1.57 (0.92–2.71)	0.10	3.00 (1.07–8.44)	0.04	2.43 (1.00–5.92)	0.05	1.11 (0.54–2.30)	0.77
FH	2.15 (1.37–3.38)	<0.001	1.67 (1.17–2.37)	<0.01	2.85 (1.40–5.79)	<0.01	1.85 (1.01–3.38)	0.05	1.49 (0.99–2.24)	0.06
Low myopia	0.97 (0.64–1.49)	0.90	0.98 (0.73–1.32)	0.89	1.24 (0.62–2.47)	0.55	0.83 (0.48–1.44)	0.51	0.93 (0.67–1.30)	0.67
High myopia	1.53 (0.80–2.95)	0.20	1.46 (0.93–2.29)	0.10	1.45 (0.44–4.75)	0.54	1.54 (0.71–3.38)	0.28	1.47 (0.90–2.39)	0.12
DBP	1.00 (0.98–1.01)	0.81	1.00 (0.99–1.01)	0.58	0.99 (0.96–1.01)	0.30	1.00 (0.99–1.02)	0.65	1.01 (0.99–1.02)	0.27
BMI	0.94 (0.89–0.99)	0.02	0.96 (0.93–0.99)	0.01	0.92 (0.84–1.01)	0.09	0.94 (0.88–1.00)	0.07	0.96 (0.93–1.00)	0.05

95% CI 95% confidence interval, BMI body-mass index, DBP diastolic blood pressure, FH positive family history for glaucoma, GON glaucomatous optic neuropathy, iGVFL incident glaucomatous visual field loss, IOP intraocular pressure, IOP Rx intraocular pressure lowering treatment