Table 3.

Mean codon frequencies (promil) in the 13 mitogenome-encoded genes of three groups of Japanese males: 97 healthy controls, 112 semi-supercentenarians and 96 centenarians from references [199], [200].

Codon	CDA	Control	Super	Cent	Codon	CDA	Control	Super	Cent
UUU	0	20.34	20.32	20.34	UAU	0.00	12.11	12.13	12.15
UUC	0.5	36.59	36.61	36.60	UAC	− 0.50	23.39	23.35	23.35
UUA	1	19.07	19.04	19.01	UAA	− 1.00	2.09	2.09	2.10
UUG	1	4.59	4.57	4.57	UAG	− 0.50	0.81	0.81	0.80
CUU	− 0.5	17.02	17.03	17.00	CAU	0.50	4.71	4.71	4.71
CUC	0	43.89	43.88	43.89	CAC	0.00	20.80	20.80	20.79
CUA	0.5	72.88	72.87	72.90	CAA	− 1.00	21.61	21.61	21.59
CUG	0.5	11.74	11.78	11.79	CAG	− 0.50	2.08	2.09	2.10
AUU	− 1	33.06	33.03	33.07	AAU	1.00	8.38	8.39	8.41
AUC	− 0.5	51.34	51.30	51.25	AAC	1.00	34.72	34.74	34.72
AUA	0	43.77	43.81	43.82	AAA	0.00	22.37	22.40	22.39
AUG	− 0.5	10.72	10.74	10.73	AAG	0.50	2.63	2.61	2.61
GUU	− 1	8.19	8.19	8.18	GAU	0.50	3.89	3.92	3.93
GUC	− 0.5	12.61	12.64	12.68	GAC	0.50	13.43	13.38	13.38
GUA	0.5	18.39	18.40	18.36	GAA	− 0.50	16.87	16.85	16.86
GUG	0	4.71	4.71	4.73	GAG	0.00	6.23	6.25	6.24
UCU	0	8.42	8.42	8.41	UGU	0.00	1.30	1.30	1.31
UCC	− 0.5	25.99	25.99	26.00	UGC	0.50	4.50	4.50	4.50
UCA	0.5	21.81	21.81	21.80	UGA	− 0.50	24.48	24.46	24.42
UCG	0.5	1.80	1.79	1.80	UGG	− 1.00	2.91	2.92	2.97
CCU	0.5	10.70	10.66	10.68	CGU	− 0.50	1.80	1.80	1.80
CCC	0	31.39	31.43	31.42	CGC	0.00	6.80	6.80	6.80
CCA	1	13.71	13.71	13.72	CGA	− 0.50	7.40	7.40	7.40
CCG	1	1.78	1.78	1.78	CGG	− 1.00	0.50	0.50	0.50
ACU	− 0.5	13.41	13.39	13.43	AGU	0.50	3.70	3.69	3.69
ACC	− 1	40.44	40.45	40.36	AGC	0.50	10.26	10.27	10.29
ACA	0	34.80	34.78	34.77	AGA	0.00	0.30	0.29	0.30
ACG	0.5	2.57	2.58	2.58	AGG	− 0.50	0.30	0.30	0.30
GCU	− 0.5	11.73	11.73	11.74	GGU	1.00	6.30	6.32	6.33
GCC	− 1	32.55	32.56	32.60	GGC	1.00	22.88	22.87	22.85
GCA	− 0.5	21.60	21.58	21.60	GGA	0.50	18.00	18.02	18.03
GCG	0	2.08	2.09	2.08	GGG	0.00	8.55	8.52	8.51