Fig. 1.
Normal Na current and pathological (increased late component of INa) Na current. (A) Activation and inactivation curves. Activation curve is m3 and inactivation curve is h × j. Solid lines: Increased window for the late component of INa. Dashed lines: normal Na channel. (B) Steady state current. Solid lines: Na current with the increased window. Dashed lines: normal Na current.