Table 2.

Cytosolic buffering parameters.

Parameter	Definition	Value
BT	Total concentration of Troponin C	70 μmol/l cytosol
BSR	Total concentration of SR binding sites	47 μmol/l cytosol
BCd	Total concentration of Calmodulin binding sites	24 μmol/l cytosol
Bmem	Total concentration of membrane binding sites	15.0 μmol/l cytosol
Bsar	Total concentration of sarcolemma binding sites	42.0 μmol/l cytosol
konT	On rate for Troponin C binding	0.0327 (μM)−1(ms)−1
koffT	Off rate for Troponin C binding	0.0196 ms−1
KSR	Dissociation constant for SR binding sites	0.6 μM
KCd	Dissociation constant for Calmodulin binding sites	7 μM
K mem	Dissociation constant for membrane binding sites	0.3 μM
K sar	Dissociation constant for sarcolemma binding sites	13.0 μM