Table 4.
Parameter | Definition | Value |
---|---|---|
PCa | Constant | 0.00054 cm/s |
gCa | Strength of Ca current flux | 182 mmol/(cm C) |
Strength of local Ca flux due to L-type Ca channels | 9000 mmol/(cm C) | |
Strength of local Ca flux due to RyR channels | 26842 mmol/(cm C) | |
kp° | Threshold for Ca-induced inactivation | 3.0 μM |
Threshold for Ca dependence of transition rate k6 | 6.1 μM | |
τpo | Time constant of activation | 1 ms |
r1 | Opening rate | 0.3 ms−1 |
r2 | Closing rate | 3 ms−1 |
s1′ | Inactivation rate | 0.00195 ms−1 |
k1′ | Inactivation rate | 0.00413 ms−1 |
k2 | Inactivation rate | 0.0001 ms−1 |
k21′ | Inactivation rate | 0.00224 ms−1 |
TBa | Time constant | 450 ms |