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. 2017 Sep 4;8:1046. doi: 10.3389/fimmu.2017.01046

Figure 5.

Figure 5

Mesenteric ischemia and ischemia followed by reperfusion enhances tissue damage in wild-type (BALB/c) mice and C3aR1-deficient mice (C3aR1 KO). H&E-stained sections of sham-operated small intestine from BALB/c mice (A) and C3aR1 KO mice (B). Mice were subjected to superior mesenteric artery occlusion for 30 min (I 30 min) to induce ischemia in BALB/c mice (C), and C3aR1 KO mice (D) followed by 120 min reperfusion (IR 30/120 min) in BALB/c mice (E), and C3aR1 KO mice (F). Scale bars, 100 µm. Cumulative data of injury scores derived from three independent experiments on separate days (three mice per group) are shown in (G). Error bars represent SD.