Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Sep 4;8:77. doi: 10.3389/fpsyt.2017.00077

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017 Rahman, Zavitsanou, Purves-Tyson, Harms, Meehan, Schall, Todd, Hodgson, Michie and Weickert.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

NR2A:NR2B binding ratio in hippocampus of adult offspring exposed to vehicle (control; black) or polyI:C (gray) during early (GD10) or late (GD19) gestation. Tritiated CGP39653 and Ifenprodil were used to calculate the ratio of NR2A:NR2B subunit binding. (A) The ratio of NR2A:NR2B ratio binding in the hippocampus was significantly increased in polyI:C offspring. (B) This increased ratio was elevated at both afferent and efferent levels of each hippocampal subregion. Bars represent mean ± SEM (n = 25–28 rats per group) (*p < 0.05).