Table 3.
Binding (fmol/mg tissue equivalent) | Mean ± SEM (n) |
|||
---|---|---|---|---|
Control | Maternal immune activation | Treatment effect | ||
N-methyl-d-aspartate receptor channel [3H]MK-801 | Cortex | 7.33 ± 0.29 (30) | 7.87 ± 0.28 (23) | F(1,45) = 1.86, p > 0.10 |
Hippocampus | 8.74 ± 0.3 (30) | 9.15 ± 0.27 (23) | F(1,45) = 1.13, p > 0.10 | |
Striatum | 6.5 ± 0.23 (29) | 7.62 ± 0.27 (25)*** | F(1,45) = 17.63, p < 0.001 | |
NR2A [3H]CGP39653 | Cortex | 2.69 ± 0.31 (28) | 4.24 ± 0.36 (25)** | F(1,45) = 11.004, p < 0.01 |
Hippocampus | 4.05 ± 0.28 (28) | 5.3 ± 0.42 (25)* | F(1,44) = 6.22, p < 0.05 | |
Striatum | 1.69 ± 0.14 (26) | 2.3 ± 0.22 (25)* | F(1,47) = 6.62, p < 0.05 | |
NR2B [3H]Ifenprodil | Cortex | 11.03 ± 0.36 (31) | 10.77 ± 0.32 (27) | F(1,50) = 0.24, p > 0.10 |
Hippocampus | 13.81 ± 0.38 (31) | 13.58 ± 0.35 (25) | F(1,48) = 0.11, p > 0.10 | |
Striatum | 13.26 ± 0.6 (30) | 13.14 ± 0.5 (24) | F(1,47) = 0.08, p > 0.10 |
*p < 0.05
**p < 0.01
***p < 0.001