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. 2017 Sep 4;8:77. doi: 10.3389/fpsyt.2017.00077

Table 3.

Overall effect of gestational polyI:C exposure on NMDA receptor channel and subunit binding.

Binding (fmol/mg tissue equivalent) Mean ± SEM (n)
Control Maternal immune activation Treatment effect
N-methyl-d-aspartate receptor channel [3H]MK-801 Cortex 7.33 ± 0.29 (30) 7.87 ± 0.28 (23) F(1,45) = 1.86, p > 0.10
Hippocampus 8.74 ± 0.3 (30) 9.15 ± 0.27 (23) F(1,45) = 1.13, p > 0.10
Striatum 6.5 ± 0.23 (29) 7.62 ± 0.27 (25)*** F(1,45) = 17.63, p < 0.001
NR2A [3H]CGP39653 Cortex 2.69 ± 0.31 (28) 4.24 ± 0.36 (25)** F(1,45) = 11.004, p < 0.01
Hippocampus 4.05 ± 0.28 (28) 5.3 ± 0.42 (25)* F(1,44) = 6.22, p < 0.05
Striatum 1.69 ± 0.14 (26) 2.3 ± 0.22 (25)* F(1,47) = 6.62, p < 0.05
NR2B [3H]Ifenprodil Cortex 11.03 ± 0.36 (31) 10.77 ± 0.32 (27) F(1,50) = 0.24, p > 0.10
Hippocampus 13.81 ± 0.38 (31) 13.58 ± 0.35 (25) F(1,48) = 0.11, p > 0.10
Striatum 13.26 ± 0.6 (30) 13.14 ± 0.5 (24) F(1,47) = 0.08, p > 0.10

*p < 0.05

**p < 0.01

***p < 0.001