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. 2017 Sep 4;8:1079. doi: 10.3389/fimmu.2017.01079

Table 1.

Distribution of CCR1, CCR3, and CCR5 in astrocytes and neurons in the central nervous system (CNS) of mammals.

Cell types CNS region Species mRNA Protein Reference
CCR1 Neurons Cultured neurons Human + (67)
Fetal brain Macacque (68)
Cerebellum Rat (27)
Hippocampus Rat + (25)
Neonatal and adult cerebellum Rat + (69)
Neonatal and adult cerebellum Rat + (70)
Cortical nerve endings Human (71)
Cortical and spinal cord nerve endings Mouse (66, 72)

Astrocytes Neonatal brain Mouse + (73)
Neonatal brain Mouse + + (74)
Fetal brain Human + (75)
Neonatal and adult cerebellum Rat + + (69)
Neonatal and adult cerebellum Rat + + (70)
Spinal cord gliosomes Mouse + (66)

CCR3 Neurons Cerebellar neurons Rat + (27)
Cortical neurons Fetal human + (29)
Fetal macaque + (29)
Cortical nerve endings Human + (71)
Cortical and spinal cord nerve endings Mouse + (66, 72)
Fetal brain neurons Human + (20)

Astrocytes Primary astrocytes Human + + (62)
Fetal and adult astrocytes Human, macaque + + (76)
Spinal cord gliosomes Mouse + (66)
Fetal brain astrocytes Human + (20)

CCR5 Neurons Neonatal DRG Rat + (68)
Cerebellar neurons Rat + (27)
Cortical neurons Fetal human + (29)
Fetal macaque + (29)
Hippocampal neurons Rat + (25)
Embryonic neurons Human + (26)
Cortical nerve endings Human + (71)
Cortical and spinal cord nerve endings Mouse + (66, 72)
Neonatal brain Rat + + (48)
Brain Human + (33)

Astrocytes Cortical astrocytes Fetal human + (29)
Fetal macaque + (29)
Fetal brain neurons Human + (20)
Fetal and adult astrocytes Human + (76)
Spinal cord gliosomes Mouse + (66)
Neonatal brain Rat + + (48)
Brain Human + (33)