Figure 6.

Comparison of LGK974 and IWP-2 drug sensitivity of breast cancer endocrine-resistant cell lines. IC₅₀ values (50% inhibition of thymidine incorporation relative to non-drug-treated cells) for LGK974 and IWP-2 are represented on the y-axis and individual cell lines on the x-axis. Cell lines are colored orange for estrogen receptor-positive status (ER). Results are shown as the mean ± SE from triplicate experiments. IC₅₀ values for LGK974 and IWP-2 were not significantly correlated (Spearman’s rank correlation coefficient, r = 0.28; p = 0.33).