Fig. 1.

Representative naturally occurring enediynes. (a) The nine-membered enediynes: C-1027 (1), neocarzinostatin (2), maduropeptin (3), kedarcidin (4), N1999A2 (5) and putative members sporolide A (6) and cyanosporaside A (7). (B) The 10-membered enediynes: dynemicin A (8), calicheamicin ${\mathrm{\gamma }}_1^{\mathrm{I}}$ (9), esperamicin A₁ (10), namenamicin (11), shishijimicin A (12), uncialamycin (13), deoxydynemicin A (14), dynemicin N (15), dynemicin O (16), dynemicin P (17), dynemicin Q (18).