Table-4.

The list of gene in mammary gland and their clinical relevance (adapted from Roosen et al., [31]).

Gene	Expressed tissue/cell	Lactating status and clinical finding (or) treatment^#
LAP	MGT* MSC@	J-H, L-H, L-I, NL-H* HCD diet^
TAP	MGT* MEC#	L-H*, S. aureus in vitro challenge#
DEFB3	MGT* MSC@	L-H*, NL-I*
DEFB4	MGTθ* MSC@	L-I*, S. aureus in vivo challengeθ
DEFB5	MGTθ* MSC@	L-I*, S. aureus in vivo challengeθ
DEFB1	MGTθ	S. aureus in vivo challengeθ
DEFB103	Other than mammary gland**	NA

^*Roosen et al., [31],

^#Lopez-Meza et al., [44],

^@Bagnicka et al., [53],

^{^}Jin et al., [41],

^θCormac et al., [50],

^**Mirabzadeh-Ardakani et al., [59]. TAP=Tracheal antimicrobial peptide, LAP=Lingual antimicrobial peptide, DEFB3=β-defensin 3, DEFB4=β-defensin 4, DEFB5=β-defensin 5, DEFB1=β-defensin 1, DEFB103=β-defensin 103, MGT=Mammary gland tissue, MSC=Milk somatic cells, J=Juvenile, L=Lactating, NL=Non-lactating, H=Healthy, I=Infected, S. aureus=Staphylococcus aureus