Table 4.
Multivariate logistic regression analysis for factors associated with amputation – data are n (%), unless otherwise specified
| Lower extremity amputation | Multivariate logistic regression analysis | ||||
|---|---|---|---|---|---|
| Risk Factor | Yes | No | |||
| n | 46 | 404 | aOR | 95% CI | P-value* |
| Previous foot ulceration | 44 (95.7) | 53 (13.1) | 167.24 | 23.22 to 1204.49 | <0.001* |
| Current foot ulceration | 26 (56.5) | 19 (4.7) | 7.49 | 1.89 to 29.69 | 0.004* |
| Foot deformity | 42 (91.3) | 299 (74.0) | 15.28 | 2.23 to 104.55 | 0.005* |
| Diabetes mellitus | 43 (93.5) | 183 (45.3) | 5.28 | 0.22 to 129.47 | 0.31 |
| Osteoarthritis | 15 (32.6) | 177 (43.8) | 0.26 | 0.07 to 1.03 | 0.055 |
aOR Adjusted odds ratio. CI Confidence interval. *Significant association, p < 0.05. The final multivariate model controlled for the following confounding variables: age, sex, physical component score, dialysis duration, retinopathy, ischemic heart disease, C-reactive protein, serum albumin, serum phosphate, glycated hemoglobin, peripheral neuropathy, peripheral arterial disease, inappropriate/ill-fitting footwear, nail pathology, and podiatry attendance