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. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Curr Opin Cell Biol. 2017 Apr 1;48:10–16. doi: 10.1016/j.ceb.2017.03.005

Figure 1. Regeneration in wing-imaginal discs.

Figure 1

(A) Regeneration following physical fragmentation of a disc that has been implanted in an adult abdomen. Wound healing (gray arrows) is facilitated by actin cables and filopodia in regions of JNK activation (green). Damaged-induced proliferation (red) occurs prior to the completion of wound healing.

(B) Genetic ablation of tissue in the wing disc. Expression of a pro-apoptotic gene (blue) during the ablation phase (30°C) eliminates most of the pouch. Regenerative growth restores the pouch that can differentiate into a wing of normal size and shape.

(C) Summary of regulators implicated in imaginal disc regeneration.