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. 2017 Sep 5;5:194. doi: 10.3389/fped.2017.00194

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Copyright © 2017 Iwatani, Harahap, Nurputra, Tairaku, Shono, Kurokawa, Yamana, Thwin, Yoshida, Mizobuchi, Koda, Fujioka, Taniguchi-Ikeda, Yamada, Morioka, Iijima, Nishio and Nishimura.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Survival motor neuron (SMN) mRNA expression in umbilical cord-derived mesenchymal stem cells (UC-MSCs) and fibroblasts (FBs) at steady state. Relative expression of total-SMN (A), FL-SMN (B), and Δ7-SMN (C) mRNA in UC-MSC-Control, UC-MSC-spinal muscular atrophy (SMA), FB-Control, and FB-SMA was analyzed by RT-qPCR and FL/Δ7-SMN ratio (D) was calculated. The expression in UC-MSC-Control and FB-Control was defined as 1. The results were expressed as the mean ± SD.