Table 3.
Summary of the patient demographics
| Variable | Study 25803 | Study 26127 | Study 26486 | Study 25643 | Overall |
|---|---|---|---|---|---|
| Age, years | |||||
| Median | 36 | 29.5 | 48.5 | 40 | 40 |
| Range | 27–54 | 20–58 | 32–54 | 19–65 | 19–65 |
| Body weight, kg | |||||
| Median | 77.5 | 70.5 | 69.5 | 68.9 | 69.2 |
| Range | 51–99 | 54–97 | 50–93 | 48.5–116.1 | 48.5–116.1 |
| Sex [n (%)] | |||||
| Male | 10 (62.5) | 4 (25) | 6 (37.5) | 39 (31.2) | 59 (34.1) |
| Female | 6 (37.5) | 12 (75) | 10 (62.5) | 86 (68.8) | 114 (65.9) |
| CLCR, mL/min | |||||
| Median | 109.2 | 121.2 | 103.7 | 105.8 | 107.9 |
| Range | 70.2–139.8 | 94.9–150.8 | 67.1–164.9 | 49.6–244.4 | 49.6–244.4 |
CL CR creatinine clearance