Table 2.
Odds ratio and 95% confidence interval of Alzheimer’s disease associated with tamoxifen use, aromatase inhibitors use, and comorbidities.
| Variable | OR† | (95%CI) |
|---|---|---|
| Age (per 1 year) | 1.02 | (0.99, 1.05) |
| Tamoxifen (never use as a reference) | ||
| Ever use | 3.09 | (2.10, 4.55) |
| Aromatase inhibitors (never use as a reference) | ||
| Ever use | 1.42 | (0.90, 2.24) |
| Comorbidities (yes vs. no) | ||
| Alcohol-related disease | 1.32 | (0.14, 12.8) |
| Cerebrovascular disease | 1.08 | (0.66, 1.75) |
| Chronic kidney disease | 1.06 | (0.55, 2.05) |
| Chronic obstructive pulmonary disease | 1.01 | (0.69, 1.46) |
| Diabetes mellitus | 1.01 | (0.71, 1.42) |
| Hyperlipidemia | 1.02 | (0.73, 1.43) |
| Hypertension | 1.01 | (0.65, 1.58) |
†Because no other variable was significantly related to Alzheimer’s disease in a univariable logistic regression model, we did not perform a multivariable logistic regression model.