Skip to main content
. 2017 Sep 5;8:619. doi: 10.3389/fphar.2017.00619

FIGURE 1.

FIGURE 1

Cytotoxicity of (±)-8-ADC on IEC6 cells and effect on transcriptional activation of XBP1. (A) The chemical structure of (±)-8-ADC and its patent number (CN104211709A). Patent details can be found in the Supporting Information. (B) IEC6 cell cytotoxicity from (±)-8-ADC measured using the CCK8 assay (n = 3). (C) Effect of (±)-8-ADC on XBP1 transcriptional activation. C refers to the background contrast and C1 to the pGL3-basic vector control. ##p < 0.01 compared with the C group; ∗∗p < 0.01 compared with the C1 group.