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. 2017 Sep 5;8:1697. doi: 10.3389/fmicb.2017.01697

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Copyright © 2017 Tian, Wang, Zhang, Luo, Jiang, Zhang, Mei, Wu, Wu, Peng, Long, Luo and Guo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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GD-SH-01 and rHEP-shP induce significantly greater apoptosis than HEP-Flury via the intrinsic apoptotic pathway. NA cells were infected with GD-SH-01, HEP-Flury, rHEP-shP, or rGDSH-P. (A) Caspase-3, caspase-8, and caspase-9 activities. (B) The relative expression of caspase-3 and caspase-9 as determined by means of RT-qPCR. (C) Protein contents of caspase-3, caspase-9, and cleaved PARP as measured by WB. β-Actin was used as a loading control. Data are represented as means ± SD of three independent experiments. One-way ANOVA followed by Bonferroni’s multiple comparison test. ^∗p < 0.05.