Table 3.

The basal and peak levels of neuro chemicals in rat brain from PLF (80 or 160 mg/kg) treated or vehicle group.

Group	1 (80 mg/kg)		2 (160 mg/kg)		3 (Vehicle)		Statistics
	Concentration (ng/mL)
Neuro chemical	Basal level (before dose)	Peak level (post dose)	Basal level (before dose)	Peak level (post dose)	Basal level (before dose)	Peak level (post dose)	df	F	P
DA	81.87 ± 15.16	46.88 ± 7.16**	85.07 ± 15.06	75.16 ± 14.29	62.38 ± 8.16	58.03 ± 3.52	2	44.96	<0.001
HVA	2320.78 ± 489.04	1611.73 ± 370.66*	1633.95 ± 300.06	2405.03 ± 433.63*	535.32 ± 53.71	462.38 ± 71.74	2	247.38	<0.001
5-HT	55.94 ± 8.42	69.79 ± 8.07	64.99 ± 11.42	73.10 ± 20.61	78.51 ± 11.94	84.12 ± 4.25	2	141.16	<0.001
5-HIAA	528.96 ± 88.06	331.72 ± 28.17**	653.41 ± 162.77	987.40 ± 125.32**	284.91 ± 31.21	319.84 ± 18.82	2	156.68	<0.001
GLu	3097.42 ± 519.40	2278.02 ± 647.76	3564.58 ± 1558.16	1202.71 ± 762.13**	9224.44 ± 1658.01	8035.41 ± 2245.20	2	770.95	<0.001
GABA	154.88 ± 10.01	194.84 ± 27.59*	220.20 ± 43.13	225.95 ± 61.95	98.70 ± 27.42	85.62 ± 16.40	2	406.29	<0.001
ACH	32.34 ± 5.65	30.65 ± 6.29	39.23 ± 10.92	62.29 ± 14.10*	19.24 ± 0.81	21.81 ± 2.69	2	133.385	<0.001

All data are expressed as Mean ± SD (n = 5).The main effect df, F and P-value were obtained through two-way analysis of variance followed by Fisher's least to test the statistical significance of difference between groups.

Compared to basal level (

^*P < 0.05,

^**P < 0.01).