Table 1.
Patient characteristics, clinical features, and treatment outcomes ofpublished cases of Campylobacter fetus prosthetic joint infection.
| Case number/references | Year | Age in years/sex | Infected arthroplasty site | Comorbidities | Animal exposure | Time from surgery to onset of infection | Bacteremia | Surgical intervention | Therapy | Outcome |
|---|---|---|---|---|---|---|---|---|---|---|
| (1) [2] | 1986 | 70 M | Hip | Alcoholism, cirrhosis | ND | ND | ND | Replacement | Colistin, gentamicin, penicillin, doxycycline | Recovered |
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| (2) [3] | 1993 | 75 M | Hip | CLL, chronic prednisone | ND | 7 days | ND | Debridement and prosthetic retention | Imipenem + gentamicin (5 weeks), lifelong suppression with amoxicillin | Recovered |
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| (3) [4] | 1994 | 68 F | Hip | RA on prednisone | ND | Several years | ND | Bone biopsy and drainage of pus with prosthetic retention | Gentamicin, azithromycin, chloramphenicol (4 weeks) | Died from an unrelated cause |
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| (4) [5] | 2003 | 76 M | Knee | None | No | 1 week | + | No | Ceftriaxone (6 weeks), Cefuroxime (9 months) | Recovered |
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| (5) [6] | 2005 | 72 M | Hip | Alcoholism | ND | 11 months | + | Debridement and prosthetic retention | Ceftriaxone (3 weeks), Roxithromycin (3 months) | Recovered |
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| (6) [7] | 2005 | 72 M | Bilateral Knee | None | Yes, cattle | 4 years | ND | Two-stage replacement | Gentamicin, rifampin, ciprofloxacin | Recovered |
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| (7) [8] | 2012 | 71 F | Knee | RA on rituximab and steroids, DM | ND | ND | − | ND | Clindamycin + Doxycycline (3 months) | Recovered |
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| (8) [9] | 2013 | 70 F | Knee | Cirrhosis | ND | ND | + | One-stage replacement | Amoxicillin-clavulanate (6 weeks), Ciprofloxacin + clindamycin | Died from an unrelated cause |
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| (9) [9] | 2013 | 78 F | Hip | None | ND | ND | − | Synovectomy, debridement, prosthetic retention | Clindamycin (8 weeks) + Gentamicin (2 weeks), lifelong suppression with amoxicillin | Recovered |
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| (10) [9] | 2013 | 88 M | Hip | Lung cancer | ND | ND | + | Not done | Clindamycin (4 weeks) + Gentamicin (1 week), lifelong suppression with clindamycin | Recovered |
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| (11) [9] | 2013 | 85 F | Hip | Cirrhosis | ND | ND | + | Not done | Amoxicillin (4 weeks) + Gentamicin (1 week), lifelong suppression with amoxicillin | Recovered |
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| (12) [9] | 2013 | 52 F | Knee | ND | ND | 5 months | − | One-stage replacement | Amoxicillin (6 weeks) + Clindamycin (6 weeks) | Recovered |
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| (13) [9] | 2013 | 76 F | Knee | ND | ND | ND | − | Synovectomy, debridement, prosthetic retention | Clarithromycin (12 weeks) + Gentamicin (1 week) | Recovered |
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| (14) [9] | 2013 | 75 M | Hip | Renal transplant | ND | 4 days | + | One-stage replacement | Clarithromycin (12 weeks) + Gentamicin (1 week) | Recovered |
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| (15) [10] | 2016 | 77 F | Knee | ND | ND | 15 days | ND | ND | ND | Recovered |
ND: not documented, M: male, F: female, CLL: chronic lymphocytic leukemia, RA: rheumatoid arthritis, and DM: diabetes mellitus.