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Effect of acute systemic administration of LY2444296 (0, 1, 3 mg/kg) on A) time spent in the open arms, B) latency to the first entrance into an open arm, C) total number of entries in the closed arms, in cocaine naïve group-housed (n= 9–10/group; left graphs) and single-housed rats (n= 8/group; right graphs) tested in a 5-min EPM test. All panels show the Mean ±SEM. *** p<0.001, ** p<0.01 versus group-housed rats (ANOVA).
