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. 2017 Sep 5;8:648. doi: 10.3389/fphys.2017.00648

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Copyright © 2017 Martínez-Micaelo, Beltrán-Debón, Aragonés, Faiges and Alegret.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Genomic region enrichment analysis of the miRNA co-expression network. (A) The locus of each of the miRNAs included in the co-expression network was mapped in the chromosome ideograms to visualize the genomic loci of co-expressed miRNAs. (B) Detailed genomic localization of the co-expressed miRNAs located on chromosome 14. The genomic region overrepresentation was corroborated by the results of a hypergeometric test (p = 1.9 × 10⁻⁷). (C) The miRNAs located in the 14q32 locus are highlighted within the miRNA co-expression network.