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. 2017 Sep 5;11:269. doi: 10.3389/fncel.2017.00269

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Copyright © 2017 Arumugam, Garcera, Soler and Tabares.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Glutamate receptor blockers do not change the density of sodium and potassium currents in NSC-34 cells. (A–C) Examples of families of total whole-cell currents in NSC-34 cells (left) and I/V curves show no significant differences in outward or inward current amplitudes among cells recorded in the absence of drugs (A); n = 13, in the presence of APV (100 μM) + CNQX (20 μM) during the recording (B); n = 10, and incubated for 3 days with the glutamate blockers (C); n = 11. Current amplitudes were normalized to cell size by dividing the absolute value of the peak current by the membrane capacitance.