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(a) Skin wound closure (%) of rats submitted to treatments (n = 8) Lanette, Collagenase, EH, or OR 1%, 5%, and 10% for 3, 7, and 14 days. Number of vessels in HE staining of rat skin wounds treated with Lanette, Collagenase, 10% EH, or 10% OR for 3, 7, and 14 days. ∗p < 0.05, ∗∗p < 0.01, and ∗∗∗p < 0.001, compared with Lanette group. #p < 0.05, compared with Collagenase group, using ANOVA followed by Newman-Keuls test.
