Table I.
Clinical findings in the patients with Proteus syndrome having abnormal D-Dimer levels and/or thrombosis
| Patient | Age (yrs) |
Gender | Affected limb |
DVT in affected limb |
Pulmonary Embolism |
Post- surgery |
D- dimer level (µg/ ml) |
L.A. | Protein C/S Levels |
Antithrombin III activity |
Prothrombin 20210 Mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 42 | F | R Leg | − | − | − | 0.60 | + | nl/nl | nl | − |
| 2 | 6 | M | L Leg | − | − | − | 0.69 | − | nl/nl | nl | − |
| 3 | 32 | M | R Leg | − | − | − | 0.7 | N.D. | N.D. | N.D. | N.D. |
| 4 | 18 | M | R Leg | + | + | + | 1.14 | N.D. | N.D. | N.D. | + |
| 5 | 14 | F | L Leg | + | − | + | 2.09 | − | Low/low | Mildly low | − |
| 6 | 6 | F | R Leg | − | + | + | 2.17 | − | Low/nl | nl | − |
| 7 | 17 | M | R Leg | + | + | + | 2.64 | N.D. | N.D. | N.D. | N.D. |
| 8 | 54 | M | Bil Legs L>R | −* | − | − | 3.19 | − | Low/nl | − | − |
| 9 | 16 | M | L Leg | + | − | + | N.D. | + | N.D. | N.D. | N.D. |
| 10 | 21 | M | L Leg | + | + | + | N.D. | N.D. | N.D. | N.D. | N.D. |
−, none; +, present;
*
, recurrent superficial thrombi;
abnl, abnormal; Bil, bilateral; DVT, Deep venous thrombosis; L, left; L.A. Lupus Anticoagulant; lat, laterality; N.D., Not done; nl, normal; R, right; yrs, years