Table 2.
A comparison of initial plasma biomarkers in MCI→MCI and MCI→DEM subjects from the Miami cohort
| MCI → MCI | MCI → DEM | Percent change | |
|---|---|---|---|
| (n = 15) | (n = 9) | (%) | |
| Cytokines (pg/ml) | |||
| TNF-α | 0.65±0.07 | 0.73±0.11 | +12 |
| IFN-γ | 5.95±1.28 | 4.62±1.6 | −22 |
| IL-1α | 1.09±0.15 | 0.91±0.14 | −16 |
| IL-17 | 13.1±5.1 | 17.8±15.4 | +35 |
| ENA-78 | 72.1±10.3 | 74.4±11.3 | +3 |
| IP-10 | 71.1±8.3 | 90.8±12.2 | +28 |
| PDGF BB | 5.53±1.42 | 7.21±2.2 | +30 |
| MCP-1 | 2.11±0.34 | 2.42±0.33 | +15 |
| Growth factors | |||
| NGF (pg/ml) | 8.8±2.1 | 2.95±0.5 | −66 |
| IgGs (pg/ml) | |||
| IgG1 | 7147±800 | 6512±519 | −9 |
| IgG2 | 85±20 | 58±17 | −31 |
| IgG3 | 1288±139 | 1700±334 | +32 |
| IgG4 | 718±174 | 592±278 | −17 |
| Amyloid-β (pg/ml) | |||
| Aβ1-40 | 213±18 | 235±20 | +10 |
| Aβ1-42 | 28±2 | 25±4 | −11 |