Table 3.
Bivariable and multivariable linear regression of factors associated with HCV knowledge and willingness to undertake treatment among HCV-positive people who inject drugs in Vancouver, Canada (2014–2015).
| Characteristic | Knowledge (n = 630) |
Willingness (n = 584) |
||
|---|---|---|---|---|
| Unadjusted Model Estimate (β) (95% CI)a |
Adjusted Model Estimate (β) (95% CI)a |
Unadjusted Model Estimate (β) (95% CI)a |
Adjusted Model Estimate (β) (95% CI)a |
|
| Age (per year older) | 0.0001 (−0.02,0.02) | 0.0004 (−0.01, 0.01) | ||
| Male (yes vs. no) | 0.42 (0.07,0.77) | 0.28 (0.02, 0.55) | ||
| Caucasian ancestry (yes vs. no) | 0.67 (0.34,1.01))** | 0.50 (0.17, 0.82)* | 0.09 (−0.16, 0.35) | |
| ≥High school education (yes vs. no) | 0.29 (−0.06, 0.61) | −0.13 (−0.38, 0.12) | ||
| Homelessb (yes vs. no) | −0.01 (−0.19, 0.46) | −0.02 (−0.37, 0.33) | ||
| Downtown Eastside residenceb (yes vs. no) | −0.68 (−1.0, −.035)** | −0.48 (−0.81, −0.15)* | −0.40 (−0.65, −0.15)** | −0.31 (−0.56, −0.06)* |
| Employmentb (yes vs. no) | 0.86 (0.48, 1.24)** | 0.76 (0.38, 1.13)** | 0.27 (−0.02, 0.56) | |
| ≥Daily crack smokingb (yes vs. no) | −0.01 (−0.56, 0.53) | −0.55 (−0.96, −0.15)* | −0.52 (−0.92, −0.13)* | |
| ≥Daily heroin injectionb (yes vs. no) | −0.30 (−0.70, 0.11) | −0.14 (−0.45, 0.16) | ||
| ≥Daily cocaine injectionb (yes vs. no) | −0.27 (−1.02, 0.47) | 0.24 (−0.30, 0.78) | ||
| Heavy alcohol useb (yes vs. no) | 0.14 (−0.35, 0.64) | 0.44 (0.06, 0.82) | ||
| Years of IDU (per year longer) | 0.005 (−0.01, 0.02) | −0.003 (−0.01, 0.01) | ||
| Accessed health or social servicesb (yes vs. no) | 0.26 (−0.16, 0.67) | 0.21 (−0.10, 0.53) | ||
| OAT (yes vs. no) | 0.02 (−0.31, 0.36) | 0.01 (−0.24, 0.26) | ||
| HIV seropositive (yes vs. no) | −0.04 (−0.37, 0.30) | 0.23 (−0.02, 0.48) | ||
| ART adherence <95% vs. HIV negative | 0.17 (−0.28, 0.62) | 0.15 (−0.19, 0.49) | ||
| ART adherence ≥95% vs. HIV negative | −0.17 (−0.56, 0.22) | 0.28 (−0.02, 0.57) | ||
| History of mental health disorder (yes vs. no) | 0.46 (0.11, 0.80)* | 0.44 (0.11, 0.78)* | 0.12 (−0.14, 0.38) | |
| Previous HCV treatment (yes vs. no) | 1.08 (0.59, 1.57)** | 0.94 (0.46, 1.43)** | 0.64 (0.11, 1.18)* | |
| HCV Knowledge (per score increase) | – | – | 0.13 (0.08, 0.18)** | 0.12 (0.07, 0.17)** |
HIV: human immunodeficiency virus. OAT: opioid agonist therapy. IDU: injection drug use. HCV: hepatitis C virus.