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. 2017 Sep 6;8:607. doi: 10.3389/fphar.2017.00607

Table 4.

AE/biotech drug association reported more than once during the study period by Clinical Units.

Onco-hematology Rheumatology Hepato-gastroenterology Dermatology Neurology
Abatacept Insomnia
Adalimumab Infusion reactions, URTI, insomnia Generalized pain, myalgia, Infusion reactions Skin eruption
Bevacizumab Paresthesia, neutropenia, asthenia
Brentuximab Paresthesia, neuropathy, diarrhea, headache, cough
Certolizumab pegol Flu-like syndrome
Cetuximab Rash, diarrhea, skin fissures
Eculizumab Myalgia, constipation
Etanercept Myalgia, peripheral edema Hypertension
Golimumab URTI
Infliximab Generalized edema, bone or joint pain Headache, dizziness, tachycardia
Natalizumab Headache
Panitumumab Rash, skin toxicity
Rituximab Paresthesia, nausea, asthenia Purpura
Tocilizumab Itch, abdominal pain, dyspnea, leukopenia, rash
Trastuzumab Asthenia, neutropenia, diarrhea

URTI, upper respiratory tract infection.