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. 2017 Sep 6;8:618. doi: 10.3389/fphar.2017.00618

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Copyright © 2017 Liang, Liu, Yeung, Li, Ip and Mak.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of EGCG on CINC-1 and MCP-1 levels in serum and BALF of rats. Both CINC-1 and MCP-1 levels in serum and BALF were significantly elevated in the rats exposed to CS for 56 days (A–D). EGCG attenuated CS-induced CINC-1 elevation in serum (A) and BALF (C) and reduced serum MCP-1 level (B) but not BALF MCP-1 level (D). The results are expressed as means ± SEM; n = 7 each group. SA group, water/sham air; CS group, water/cigarette smoke; EGCG/SA group, EGCG (50 mg/kg)/sham air; EGCG/CS, EGCG (50 mg/kg)/cigarette smoke. ^∗p < 0.05 and ^∗∗∗p < 0.001 for the comparison between CS and SA group, ^#p < 0.05 for the comparison between EGCG/CS and CS group.