Table 2.
CFR meta-estimates and number of in-hospital deaths in children with RSV-ALRI in children younger than 5 years in 2015, by World Bank Income regions
| Low income | Lower-middle income | Upper-middle income | High income | Developing countries | Industrialised countries | Global*† | ||
|---|---|---|---|---|---|---|---|---|
| Studies | 9 | 16 | 12 | 6 | 41 | 2 | 43 | |
| 0–5 months | ||||||||
| hCFR (%)‡ | 1·7 (0·4–6·8) | 2·7 (2·0–3·6) | 1·8 (1·2–2·6) | 0·2 (0·0–12·8) | 2·2 (1·8–2·7) | 0·0 (0·0–0·1) | .. | |
| Number of deaths‡§ | 1300 (200–7900) | 20 000 (13 500–29 500) | 7200 (4200–12 300) | 400 (1–228 200) | 27 100 (20 700–35 500) | <50 (0–2000) | 27 300 (20 700–36 200) | |
| 6–11 months | ||||||||
| hCFR (%)‡ | 9·3 (3·0–28·7) | 2·8 (1·8–4·4) | 2·4 (1·1–5·4) | 0·9 (0·2–4·0) | 2·4 (1·9–3·2) | 0·1 (0·0–0·4) | .. | |
| Number of deaths§‡ | 3400 (400–26 600) | 10 300 (4800–21 600) | 8000 (2800–22 100) | 900 (200–4600) | 16 500 (10 400–25 800) | <50 (0–300) | 16 500 (10 500–26 100) | |
| 12–59 months | ||||||||
| hCFR (%)‡ | 4·7 (0·7–33·7) | 2·7 (1·7–4·3) | 0·5 (0·1–3·5) | 0·7 (0·1–5·2) | 2·2 (1·6–3·0) | 0·1 (0·0–0·3) | .. | |
| Number of deaths§‡ | 1400 (100–16 100) | 12 300 (6500–23 100) | 1500 (200–11 700) | 700 (100–5600) | 15 300 (9500–25 000) | 100 (0–300) | 15 400 (9500–24 900) | |
| 0–59 months | ||||||||
| Number of deaths‡§ | 8200 (2200–36 900) | 43 600 (31 400–60 400) | 17 900 (10 300–34 500) | 3300 (700–231 100) | 59 600 (47 800–74 300) | 200 (100–2200) | 59 600 (48 000–74 500) | |
RSV=respiratory syncytial virus. ALRI=acute lower respiratory infection. hCFR=in-hospital CFR. hCFR and number of deaths are presented with 95% CI.
Global total for a given age band is sum of the deaths in developing and industrialised countries. We have taken this more conservative approach because there are only a small number of studies contributing to deaths by World Bank income region in narrow age bands leading to large uncertainties in some of these estimates.
Although the overall number of deaths was obtained by summing the age and region-specific numbers for each of the 10 000 samples in the Monte Carlo simulation, the point estimates and uncertainty interval limits for the overall deaths are not equal to the sum of the age and region-specific results. This reflects the fact that the overall estimates are determined by the full uncertainty distributions for each age and region-specific estimates, and not simply the point estimates.
Data in parentheses are 95% CI.
The number of deaths has been rounded to the nearest hundreds.