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. 2017 Jul 14;121(35):8211–8241. doi: 10.1021/acs.jpcb.7b03441

Figure 15.

Figure 15

Distances estimated by time-resolved fluorescence measurements for the simplest bimodal model of two discrete distances are highly correlated. (A) Correlation coefficients Inline graphic. (B, left) The 2D probability distribution function (counterfeit normal) of observed estimates of parameters Inline graphic, Inline graphic for expectations Inline graphic, Inline graphic. (B, right) The marginal (1D projections) probability distribution functions of estimations of Inline graphic (blue), Inline graphic (green), and the probability distribution functions of ΔRDA estimation (red, shifted for comparison) for 4 sets of expected parameters marked by circles in Figure 14A,B and here in panel A. Indices (i, ii, iii) correspond to the regions defined in Figure 14B.