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. 2017 Jul 19;292(36):14786–14795. doi: 10.1074/jbc.M117.786160

Figure 7.

Figure 7.

p62 regulates PGE2 production but not proliferation or migration in vitro. A, PGE2 production in PAM212 cells stably transfected with shCon or shp62. shp62 cells were transiently transfected with COX-2 (shp62+COX-2). n.s., not significant; *, p < 0.05; **, p < 0.01. B, PGE2 production in HeLa cells transiently transfected with EV, HA–p62, COX-2, and HA–p62–dUBA, as indicated. n.s., not significant; *, p < 0.05; **, p < 0.01. C, proliferation of PAM212 cells stably transfected with shCon or shp62 measured over 3 days using an MTS proliferation assay. D, migration of WT, shCon, and shp62 PAM212 cells measured using a Transwell migration assay in serum-free medium. Error bars, S.D.