Figure 4.

Histologic analysis of retinas of P30 Exoc5 conditional mice. A and B, transverse retina cryosections of WT (A) and photoreceptor-specific Exoc5 knock-out (Exoc5 fl/fl; Rho-Cre⁺) (B) mice revealed a thinning of the outer retina in P30 Exoc5 conditional photoreceptor knock-out mice. Scale bars, 125 μm (A and B). RPE, retinal pigmented epithelium; OS, outer segments; IS, inner segments; ONL, outer nuclear layer; IPL, inner plexiform layer; INL, inner nuclear layer; PRL, photoreceptor layer.