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. 2017 Jul 18;292(36):14836–14850. doi: 10.1074/jbc.M116.766808

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© 2017 by The American Society for Biochemistry and Molecular Biology, Inc.

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Figure 8. — CTRP6 induces TNF-α expression and production in macrophages. A and B, increased TNF-α mRNA (A) and secreted protein (B) in RAW264.7 macrophage cell line treated with the indicated doses of recombinant CTRP6 for 6 h (n = 3/group). ***, p < 0.001 versus 0 μg/ml group. C and D, increased TNF-α mRNA (C) and secreted protein (D) in a macrophage cell line treated with the indicated doses of recombinant CTRP6 for 24 h (n = 3/group). E and F, increased TNF-α mRNA (E) and secreted protein (F) in primary BMM treated with the indicated doses of recombinant CTRP6 for 24 h (n = 4/group). *, p < 0.05; **, p < 0.01; ***, p < 0.001 versus control group. Error bars, S.E.