Figure 1.
Palmitic acid inhibits endothelial proliferation, migration, and angiogenesis. HAECs were treated with different concentrations of PA for 24 h before the following analysis. Representative images of BrdU staining (n = 5 biological repeats) (A) and flow cytometry analysis of the BrdU proliferation assay (n = 5 biological repeats) (B) showed that PA treatment induced a dose-dependent inhibition of endothelial cell proliferation. C, scratch assay showed that PA treatment induced a dose-dependent inhibition of endothelial cell migration (n = 6 biological repeats). D, Matrigel tube formation assay showed that PA reduced endothelial cell tube formation (n = 6 biological repeats).