Table 1.
Stability of dioscin and diosgenin in SGF (pH 1.2).
Incubation time (min) | Dioscin (glycoside) | Diosgenin (aglycone) | |||
---|---|---|---|---|---|
Amount of dioscin in SGF (μg/mL) | Formation of diosgenin with time (%) | % RD of dioscin depletion | Amount of diosgenin in SGF (μg/mL) | % RD of diosgenin depletion | |
0 | 45.0 ± 4.0 | – | – | 52.4 ± 0.9 | – |
30 | 37.5 ± 1.2 | 6.3 | 16.7 | 50.5 ± 0.9 | 3.62 |
60 | 34.4 ± 1.1 | 19.8 | 23.6 | 48.0 ± 1.9 | 8.31 |
120 | 32.3 ± 1.0 | 24.2 | 28.3 | 47.9 ± 1.1 | 8.59 |
Data are expressed as mean ± SD of triplicate samples from one experiment. RD = Relative difference.