Table 2.

Average c-Fos mRNA (mean optical density ± SEM) expression in adult male F344 rats.

Region	Subregion	HCC	CXT	SI	ANOVA RESULTS
Prefrontal Cortex	ACC	0.023 ± 0.011	0.076 ± 0.016^*	0.092 ± 0.009^*	F(2,16) = 8.79, p < 0.01
	PL	0.021 ± 0.008	0.082 ± 0.018^*	0.096 ± 0.011^*	F(2,16) = 9.52, p < 0.01
	IL	0.0014 ± 0.006	0.069 ± 0.014^*	0.079 ± 0.009^*	F(2,16) = 11.85, p < 0.001
	VO	0.045 ± 0.016	0.130 ± 0.026^*	0.128 ± 0.010^*	F(2,16) = 6.96, p < 0.01
	INS	0.015 ± 0.004	0.015 ± 0.003	0.012 ± 0.002	F(2,16) = 0.46, p = 0.64
Bed Nucleus of the Stria Terminalis	MA	−0.004 ± 0.001	0.027 ± 0.009^*	0.015 ± 0.004^*	F(2,17) = 7.37, p < 0.01
	LD	−0.004 ± 0.001	0.018 ± 0.007^*	0.006 ± 0.004	F(2,17) = 5.17, p < 0.05
	MV	−0.003± 0.001	0.022 ± 0.008^*	0.013 ± 0.003^*	F ( 2,17) = 7.04, p < 0.01
	LV	−0.001 ± 0.003	0.014 ± 0.003^*	0.006 ± 0.003	F(2,17) = 5.37, p < 0.05
Lateral Septum	DORSAL	−0.003 ± 0.001	0.014 ± 0.006	0.016 ± 0.008	F(2,17) = 2.56, p = 0.11
Lateral Septum	VENTRAL	−0.003 ± 0.002	0.027 ± 0.010^*	0.026 ± 0.006^*	F(2,17) = 5.95, p < 0.05
Rostral Splenial Cortex	LAYER II/III	0.060 ± 0.012	0.189 ± 0.046^*	0.179 ± 0.016^*	F(2,16) = 6.44, p < 0.01
	LAYER IV	0.030 ± 0.006	0.115 ± 0.029^*	0.117 ± 0.011^*	F(2,16) = 7.88, p < 0.01
	LAYER V/VI	0.020 ± 0.003	0.108 ± 0.034^*	0.111± 0.013^*	F(2,16) = 5.87, p < 0.05
Barrel Field Cortex	LAYER II/III	0.060 ± 0.012	0.189 ± 0.046^*	0.179 ± 0.016^*	F(2,16) = 11.58, p < 0.001
	LAYER IV	0.054 ± 0.013	0.300 ± 0.068^*	0.364 ± 0.046^*	F(2,16) = 12.68, p < 0.001
	LAYER V/VI	0.035 ± 0.006	0.219 ± 0.063^*	0.236 ± 0.045^*	F(2,16) = 6.51, p < 0.01
	MeA	0.015 ± 0.004	0.097 ± 0.032^*	0.088 ± 0.014^*	F(2,16) = 5.35, p < 0.05
	PVN	0.032 ± 0.013	0.088 ± 0.025	0.097 ± 0.020	F(2,16) = 3.06, p = 0.08
Hippocampus	CA1	0.019 ± 0.008	0.136 ± 0.048^*	0.149 ± 0.033^*	F(2,16) = 4.73, p < 0.05
	CA3	0.03 ± 0.009	0.131 ± 0.037^*	0.144 ± 0.030^*	F(2,16) = 4.81, p < 0.05
	DG	0.025 ± 0.010	0.122 ± 0.035^*	0.116 ± 0.021^*	F(2,16) = 5.60, p < 0.05

Note: All values represent optical density–background labeling.

indicates a significant difference from HCC

^{^}

indicates a significant difference from CXT.