2.

Clinic-pathological characteristics of luminal A breast cancer patients (N=421)

Factors	n (%)	Case of metastasis	5-year DFS			Case of death	5-year OS
Factors	n (%)	Case of metastasis	DFS (%)*	χ²**	P**	Case of death	OS (%)*	χ²**	P**
DFS, disease-free survival; OS, overall survival; BCS, breast conserving surgery; NAC, neoadjuvant chemotherapy; AC, adjuvant chemotherapy; ET, endocrine therapy; , DFS and OS are analyzed by Kaplan-Meier survival analysis; *, univariate analysis by log-rank test.
Age (year)				3.501	0.174			12.872	0.002
<35	8 (1.9)	0	100			0	100
35–65	293 (69.6)	7	97.5			3	98.7
>65	120 (28.5)	7	93.1			9	94.2
Menstrual status				3.762	0.520			2.426	0.119
Premenopausal	166 (39.4)	2	98.6			2	98.3
Postmenopausal	255 (60.6)	12	94.9			10	96.8
Lymph-vascular invasion				14.092	<0.001			5.957	0.015
Yes	18 (4.3)	3	80.2			2	87.1
No	403 (95.7)	11	97.0			10	97.9
Breast surgery				0.974	0.324			1.677	0.195
BCS	106 (25.2)	2	97.9			1	98.7
Mastectomy	315 (74.8)	12	95.7			11	97.0
Tumor size				11.521	0.009			23.626	<0.001
T1	263 (62.5)	3	98.6			3	99.1
T2	140 (33.3)	11	92.1			9	95.0
T3	15 (3.6)	0	100			0	100
T4	3 (0.7)	0	100			1	50.0
Lymph node status				20.532	<0.001			14.234	0.003
N0	284 (67.5)	5	99.2			7	97.9
N1	100 (23.8)	7	90.7			3	97.4
N2	29 (6.9)	0	100			0	100
N3	8 (1.9)	2	83.3			2	72.9
Grade				2.550	0.279			2.144	0.342
I	290 (68.9)	7	97.4			6	97.9
II	124 (29.5)	7	93.8			6	96.1
III	7 (1.7)	0	100			0	100
Treatment				4.287	0.117			6.179	0.046
NAC+ET	52 (12.4)	5	93.8			5	94.0
AC+ET	102 (24.2)	2	97.0			1	98.0
ET	267 (63.4)	7	96.7			6	97.2