Table 3.
Predicted sub-zero membrane permeability parameters and the optimal rates of freezing for X. helleri sperm cells in the presence of extracellular ice and cryoprotective agents (CPAs)
Assumed inactive cell volume (Vb) | Freezing media | Lpg or Lpg[cpa] × 1015 m3/Ns (μm/min atm) | ELp or ELp[cpa] kJ/mol (kcal/mol) | Goodness of fit, R2 value | Predicted optimal cooling rate (°C/min) |
---|---|---|---|---|---|
0.4Vo | HBSS | 1.13 (0.0067) | 48.90 (11.68) | 0.997 | 90 |
HBSS with 14% glycerol | 1.82 (0.0108) | 104.60 (25.01) | 0.997 | 25 | |
HBSS with 10% DMSO | 2.45 (0.0145) | 119.00 (28.45) | 0.997 | 24 | |
0.8Vo | HBSS | 0.42 (0.0025) | 62.70 (15.00) | 0.996 | 71 |
HBSS with 14% glycerol | 0.41 (0.0024) | 41.70 (9.96) | 0.962 | 20 | |
HBSS with 10% DMSO | 0.46 (0.0027) | 43.20 (10.32) | 0.966 | 25 |