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Levels of IFN-γ or CXCL10 in supernatants of PBMCs cultured with PPD or ESAT-6 from TB-IRIS or non-TB-IRIS patients. TB-IRIS patients exhibited higher levels of IFN-γ before and after ART when PBMCs were cultured with PPD but only after ART when cultured with ESAT-6 (A). TB-IRIS patients exhibited higher levels of CXCL10 at only the 6-week time point after ART when PBMCs were cultured with both PPD and ESAT-6 (B).
