Table II.

Degree, betweenness, closeness and subgraph of the top 20 nodes in the protein-protein interaction network.

Node, gene	Subgraph	Degree	Betweenness	Closeness
BDKRB1	1,515.014801	15		2.18×10−2
EDN1	1,337.5355	24	14,298.21	2.20×10−2
CXCL12	1,014.57958	14	1,799.90	2.18×10−2
ADCY4	691.12317
F2R	687.05615	11		2.18×10−2
CCR10	641.9886599	9
S1PR1	633.8678	10
CCL28	597.2848528	9
AGTR1	580.683	10		2.18×10−2
ADRA2A	559.71972
TAS2R39	559.718772
RGS4	542.425323
F2RL2	511.2666327
PLCB4	510.37097	9		2.18×10−2
PTGFR	486.30338
HTR2B	432.8887689
ARRB1	363.97263
MMP1	248.22731	11	4,609.06	2.19×10−2
IGF1	233.1976220	17	4,473.53
FOS	213.7347773	13	6,338.76	2.19×10−2
ADCY4		13	2,133.74	2.18×10−2
KIT		13	4,026.67	2.18×10−2
ITGA2		12	5,403.44	2.19×10−2
MET		12	3,152.53	2.18×10−2
PBX1		11	3,496.13
ITGA8		10
LYN		10	3,282.67	2.18×10−2
ITGA3		10	2,372.76
KLF4			4,272.19
ITGB2			3,974.00
FGF10			3,904.25
VCAM1			2,679.60
NOG			2,237.87
ARHGDIB			2,199.00
IL12A			1,979.33
F10			1,848.00
FST				2.17×10−2
BDNF				2.18×10−2
ARRB1				2.18×10−2
MME				2.18×10−2
DKK1				2.18×10−2
PGF				2.19×10−2
IGF1				2.19×10−2