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Methylation of CpG-11.12, CpG-23 and CpG-24.25 of the Pten promoter in the thymus. The control group was not treated with MNU, the tumor group was exposed to MNU and developed tumors, while the non-tumor group was exposed to MNU but did not develop tumors. *P<0.05 and **P<0.01, with comparisons indicated by lines. CpG, 5-C-phosphate-G-3; Pten, phosphatase and tensin homolog; MNU, N-methyl-N-nitrosourea..
