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. 2017 Aug 30;51(4):1115–1123. doi: 10.3892/ijo.2017.4110

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Copyright: © Cao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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lncRNA-TUG1 is upregulated in osteosarcoma and correlated with disease status. (A) TUG1 expression levels were determined by RT-qPCR in osteosarcoma tissues and adjacent normal tissues (n=25, P<0.0001). (B) The relative TUG1 expressions were analyzed in metastatic and non-metastatic osteosarcoma cells (n=25, P<0.0001). (C) TUG1 expression in different stages of osteosarcoma (n=25, P<0.0001). (D) RT-qPCR was conducted to quantify the expression of TUG1 in osteosarcoma cell lines compared with the normal cells. GAPDH gene was used as the endogenous control for mRNA. Error bars indicate s.d. ^**P<0.01, Student's t-test.