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. 2017 Aug 30;51(4):1115–1123. doi: 10.3892/ijo.2017.4110

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Copyright: © Cao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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TUG1-miR-144-3p-EZH2 axis is critical for osteosarcoma cell migration. (A) Osteosarcoma cell migration was determined by Transwell assay. TUG1 knockdown or miR-144-3p overexpression inhibited osteosarcoma cell migration, while EZH2 overexpression or miR-144-3p inhibitor reversed the above inhibition. (B) Quantification of cell migration is shown. (C) Wound healing assay was performed to analyze cell migration. TUG1 knockdown or miR-144-3p overexpression inhibited osteosarcoma cell migration, while EZH2 overexpression or miR-144-3p inhibitor reversed the above inhibition. (D) Quantification of cell migration is shown. Error bars indicate s.d. ^**P<0.01, Student's t-test.