Table I.
Diagnostic value of individual markers to distinguish malignant from benign thyroid tumors.
| Markers | AUC | Cut-off | Spe (%) | Sens (%) | PPV (%) | NPV (%) | Fisher's exact test (10−15) |
|---|---|---|---|---|---|---|---|
| Galectin-3 | 0.957 | >0 | 83 | 97 | 85 | 96 | P=1.07 |
| CK19 | 0.947 | >2 | 76 | 98 | 80 | 98 | P=1.02 |
| HBME-1 | 0.910 | >0 | 79 | 88 | 81 | 87 | P=4.20 |
| Galectin-1 | 0.883 | >0 | 97 | 80 | 96 | 83 | P=5.16 |
| TPO | 0.879 | >2 | 80 | 83 | 80 | 83 | P=345.47 |
AUC, area under the curve; Spe, specificity; Sens, sensitivity; PPV, positive predictive value; NPV, negative predictive value; CK19, cytokeratin 19; HBME-1, Hector Battifora Mesothelial Epitope-1; TPO, thyroid peroxidase.