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Downregulation of Wnt3a expression reduces the expression of MMP-2/-7/-9. The protein expression of MMPs (MMP-2/-7/-9) in MHcc97H and SK-Hep-1 cells after siRNA transfection for 24 h was examined by western blotting (A). Quantification of the expression levels of related proteins following transfection with siRNA (B–D).
