TABLE 2.

Estimated Effect of cART on CD4 Percentage,^* 790 Children Initiating HIV Care Between December 2004 and May 2010 in Kinshasa, DRC

Model	Absolute Change in CD4 Percentage From Baseline (95% CI)
	<0–6 mo of cART	<6–12 mo of cART	<18–24 mo of cART	<30–36 mo of cART	<42–48 mo of cART	<54–60 mo of cART
1. Weighted, adjusted† (baseline confounders)	6.8 (4.7–8.9)	8.6 (7.0–10.2)	12.7 (10.7–14.7)	13.4 (10.9–15.9)	15.9 (12.8–19.0)	20.5 (16.1–24.9)
2. Unweighted, unadjusted (no confounders)	0.3 (−1.5–2.2)	1.2 (−0.1–2.6)	4.0 (2.3–5.6)	3.4 (1.2–5.6)	3.6 (0.7–6.5)	3.7 (−0.5–7.8)
3. Unweighted, adjusted (baseline confounders)	4.2 (2.2–6.1)	5.7 (4.1–7.3)	9.9 (7.9–11.9)	10.8 (8.2–13.4)	12.6 (9.6–15.7)	16.3 (12.0–20.5)
4. Unweighted, adjusted (baseline and time-varying confounders)	8.4 (6.7–10.2)	8.4 (7.3–9.4)	5.0 (3.8–6.1)	3.6 (2.2–5.1)	4.2 (5.8–4.2)	4.8 (2.6–6.9)

^*All estimates are derived from repeated measures linear models, fit with generalized estimating equations, that include time modeled as a restricted cubic spline with 4 knots.

^†MSM: Weighting appropriately accounts for time-varying confounders affected by prior exposure.